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Granactive Hexapeptide

Youthful Appearance With
the "Gransil Touch"




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Features and Benefits:
  • Maximized skin regenerative properties
  • Clinical study proven wrinkle reduction
  • Great sensorial aesthetics
  • Improved skin health


INCI Name:
Cyclopentasiloxane (and) Polysilicone-11 (and) Ethoxydiglycol (and) Palmitoyl Hexapeptide-14

Recommended Use Levels:
>5%

Safety:
Non-irritating, Non-sensitizing, Non-mutagenic

Availability:
Globally

Applications:
  • Color Cosmetics
  • Daily Wear
  • Anti-Aging

   
Anti-Aging Silicone Polymer Matrix
Granactive™ Hexapeptide is a clear to translucent anhydrous gel. It is an anti-aging complex that combines the matrix-fibroblast stimulation of Palmitoyl Hexapeptide-14 with polysilicone-11. Together they instantly improve the skin feel perception during payout and transitions to that sought after powdery silicone-elastomer "Gransil touch" with a soft-focus matte appearance. Palmitoyl hexapeptide-14 is a short bioactive peptide modified with palmitoyl for enhanced delivery and has proven to be a superb ingredient for stimulating collagen production, stimulating proliferation of fibroblast cells and inhibiting MMPs.

Granactive™ Hexapeptide can be used in both emulsions and anhydrous based systems for comprehensive anti-aging function of reducing the appearance of fine lines and wrinkles, while eliminating dull and dry skin by rebuilding the extra-cellular matrix.

Peptide Gel vs RENOVA® Wrinkle/Fine Line Comparative Study
Study Aim:
A 12-week split-face, double-blind study comparing the efficacy of a palmitoyl hexapeptide-14 gel with Renova® cream 0.05% in the correction of fine lines and wrinkles. Renova® cream is PDA approved for use in the mitigation of fine facial wrinkles.

Under-Eye Wrinkle Reduction
Week 0 
Week 12 

Results:
All of the five investigators rated the peptide equal to or more effective than Renova® cream in regard to therapy for fine lines and wrinkles of the periorbital region.

Granactive Hexapeptide


INCI NAME

Cyclopentasiloxane (and) Polysilicone-11 (and) Ethoxydiglycol (and) Palmitoyl Hexapeptide-14


PHYSICAL PROPERTIES

AppearanceTranslucent gel
Viscosity at Amorphous State*
(Brookfield DV-I+ Spindle TD, 0.3rpm, 1.0min.)
58,000 - 85,000 cPs
Non-Volatile Matter, wt%
(105°C, 1.5g, 3hrs, Gravity Oven)
4.5 - 8.5
Shelf LifeOne year in a closed container
Packaging18kg pail and 180kg drum
* Viscosity measured right after mixing



Demo Formulations Available By Request